Article
Significant association of FcepsilonRIalpha promoter polymorphisms with aspirin-intolerant chronic urticaria.
The Journal of allergy and clinical immunology - 1 Feb 2007
Bae Jin-Sik, Kim Seung-Hyun, Ye Young-Min, Yoon Ho Joo, Suh Chang-Hee, Nahm Dong-Ho, Park Hae-Sim
Abstract excerpt
BACKGROUND: Although the mechanism that underlies aspirin hypersensitivity is not completely understood, an IgE-mediated response was reported for a patient with aspirin-intolerant chronic urticaria (AICU). OBJECTIVE: We investigated whether genetic polymorphisms on the alpha-chain of the high-affinity IgE receptor (FcepsilonRIalpha) gene were associated with the AICU phenotype. METHODS: We genotyped 2 promoter...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
