Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of genetic polymorphism of ALOX15 on aspirin-exacerbated respiratory disease.

International archives of allergy and immunology - 1 Jan 2012

Song Young-Sin, Yang Eun-Mi, Kim Seung-Hyun, Jin Hyun Jung, Park Hae-Sim

Abstract excerpt

BACKGROUND: Aspirin-exacerbated respiratory disease (AERD) is a clinical syndrome associated with chronic inflammation in the airways coincident with chronic rhinitis, sinusitis, recurrent polyposis and asthma. Eosinophils are the key inflammatory cells in the development of AERD. AERD has been attributed to abnormalities of the arachidonic acid metabolism, but the pathogenesis of AERD is not fully understood....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arachidonate 15-Lipoxygenase
Share to Aspirin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Asthma

Share to DNA Primers

Share to Eosinophils

Share to Leukocyte Count

Share to Republic of Korea

Share to Respiratory Hypersensitivity

Source

Identifiers

PMID: 22652554
DOI: 10.1159/000335681

Genes

ALOX15
GCG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of genetic polymorphism of ALOX15 on aspirin-exacerbated respiratory disease.PMID 22652554Read ↗

Physiopathology and genetics in aspirin-exacerbated respiratory disease.Semantic proximity Read ↗

A genetic effect of IL-5 receptor α polymorphism in patients with aspirin-exacerbated respiratory disease.Semantic proximity Read ↗

Unraveling the Genetic Basis of Aspirin Hypersensitivity in Asthma Beyond Arachidonate PathwaysSemantic proximity Read ↗

Update on recent advances in the management of aspirin exacerbated respiratory disease.Semantic proximity Read ↗

Increased expression of serine palmitoyl transferase and ORMDL3 polymorphism are associated with eosinophilic inflammation and airflow limitation in aspirin-exacerbated respiratory disease.Semantic proximity Read ↗

Genetic and Epigenetic Components of Aspirin-Exacerbated Respiratory Disease.Semantic proximity Read ↗

Association of single nucleotide polymorphisms on Interleukin 17 receptor A (IL17RA) gene with aspirin hypersensitivity in asthmatics.Semantic proximity Read ↗

Genetic variants in arachidonic acid pathway genes associated with NSAID-exacerbated respiratory disease.Semantic proximity Read ↗

Effect of single nucleotide polymorphisms within the interleukin-4 promoter on aspirin intolerance in asthmatics and interleukin-4 promoter activity.Semantic proximity Read ↗

Dipeptidyl-peptidase 10 as a genetic biomarker for the aspirin-exacerbated respiratory disease phenotype.Semantic proximity Read ↗

Aspirin-exacerbated respiratory disease: an update.Semantic proximity Read ↗

Nasal transcriptome and epigenome analysis identifies the pathogenic features of aspirin-exacerbated respiratory diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.