Article
Association of TNF-alpha promoter polymorphisms with aspirin-induced urticaria.
Journal of clinical pharmacy and therapeutics - 1 Apr 2009
Choi J H, Kim S H, Cho B Y, Lee S K, Kim S H, Suh C H, Park H S
Abstract excerpt
OBJECTIVE: Although the pathogenesis of aspirin-induced urticaria (AIU) is not fully understood, mast cell activation has been noted in patients with AIU. Tumour necrosis factor (TNF)-alpha, a potent pro-inflammatory cytokine, is released by human skin mast cells and other inflammatory cells in p...
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