Article
Association between a TGFbeta1 promoter polymorphism and the phenotype of aspirin-intolerant chronic urticaria in a Korean population.
Journal of clinical pharmacy and therapeutics - 1 Dec 2008
Park H-J, Ye Y-M, Hur G-Y, Kim S-H, Park H-S
Abstract excerpt
BACKGROUND: Chronic urticaria/angioedema is a common phenotype in patients with aspirin sensitivity; however, its genetic mechanism is not understood. Transforming growth factor (TGF)beta1 is a key regulatory cytokine involved in allergic inflammation. OBJECTIVE: We examined the association of a TGFbeta1 genetic polymorphism with aspirin-intolerant chronic urticaria (AICU) and aspirin-tolerant chronic urticaria...
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