Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A clustered ground-glass hepatocyte pattern represents a new prognostic marker for the recurrence of hepatocellular carcinoma after surgery.

Cancer - 1 Jul 2011

Tsai Hung-Wen, Lin Yih-Jyh, Lin Pin-Wen, Wu Han-Chieh, Hsu Kai-Hsi, Yen Chia-Jui, Chan Shih-Huang, Huang Wenya, Su Ih-Jen

Abstract excerpt

BACKGROUND: The recurrence of hepatocellular carcinoma (HCC) after hepatectomy is a serious event. It has been demonstrated that different ground-glass hepatocyte (GGH) patterns harbor specific hepatitis B virus (HBV) pre-S deletion mutants and represent preneoplastic lesions in chronic HBV infection. In the current study, the authors investigated whether a specific GGH pattern in nontumorous liver tissues was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Hepatocellular
Share to Hepatectomy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis B Surface Antigens

Share to Hepatitis B virus

Share to Hepatocytes

Share to Neoplasm Recurrence, Local

Share to Precancerous Conditions

Share to Viral Load

Source

Identifiers

PMID: 21692054
DOI: 10.1002/cncr.25837

Genes

GGH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A clustered ground-glass hepatocyte pattern represents a new prognostic marker for the recurrence of hepatocellular carcinoma after surgery.PMID 21692054Read ↗

Characterization of integrated hepatitis B virus DNA harboring pre-S mutations in hepatocellular carcinoma patients with ground glass hepatocytes.Semantic proximity Read ↗

Different types of ground glass hepatocytes in chronic hepatitis B virus infection contain specific pre-S mutants that may induce endoplasmic reticulum stress.Semantic proximity Read ↗

Ground glass hepatocytes contain pre-S mutants and represent preneoplastic lesions in chronic hepatitis B virus infection.Semantic proximity Read ↗

Pre-S mutant surface antigens in chronic hepatitis B virus infection induce oxidative stress and DNA damage.Semantic proximity Read ↗

HBsAg expression of liver correlates with histological activities and viral replication in chronic hepatitis B.Semantic proximity Read ↗

Hepatitis B virus pre-S2 mutant large surface protein inhibits DNA double-strand break repair and leads to genome instability in hepatocarcinogenesis.Semantic proximity Read ↗

Glutathione S-transferase A2 (GSTA2) Promotes Hepatocellular Carcinoma Recurrence After Liver Transplantation Through Modulating Reactive Oxygen Species MetabolismSemantic proximity Read ↗

ASSOCIATION BETWEEN MURINE DOUBLE MINUTE 2 - T309G polymorphism and recurrence of hepatocellular carcinoma after surgical treatment.Semantic proximity Read ↗

Hepatitis B virus pre-S mutants, endoplasmic reticulum stress and hepatocarcinogenesis.Semantic proximity Read ↗

Progenitor‐derived hepatocellular carcinoma model in the rat†Semantic proximity Read ↗

Recipient C7 rs9292795 genotype and the risk of hepatocellular carcinoma recurrence after orthotopic liver transplantation in a Han Chinese population.Semantic proximity Read ↗

Lipid Storage and Interferon Response Determine the Phenotype of Ground Glass Hepatocytes in Mice and Humans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.