Article
Different types of ground glass hepatocytes in chronic hepatitis B virus infection contain specific pre-S mutants that may induce endoplasmic reticulum stress.
The American journal of pathology - 1 Dec 2003
Wang Hui-Ching, Wu Han-Chieh, Chen Chien-Fu, Fausto Nelson, Lei Huan-Yao, Su Ih-Jen
Abstract excerpt
Ground glass hepatocyte (GGH) represents a histological hallmark of chronic hepatitis B virus infection and contains surface antigens in the endoplasmic reticulum (ER). Several types of GGHs are recognized at different hepatitis B virus replicative stages. The recent identification of pre-S mutants from GGHs encourages us to investigate whether different GGHs may harbor specific mutants and exhibit differential...
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