Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Progenitor‐derived hepatocellular carcinoma model in the rat†

4 Dec 2009

Abstract excerpt

UNLABELLED: Human hepatocellular carcinoma (HCC) is a heterogeneous disease of distinct clinical subgroups. A principal source of tumor heterogeneity may be cell type of origin, which in liver includes hepatocyte or adult stem/progenitor cells. To address this issue, we investigated the molecular mechanisms underlying the fate of the enzyme-altered preneoplastic lesions in the resistant hepatocyte (RH) model....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glutathione Transferases and Polymorphisms
Share to Hepatocellular Carcinoma Treatment and Prognosis
Share to Liver physiology and pathology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20054870
DOI: 10.1002/hep.23488

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Progenitor‐derived hepatocellular carcinoma model in the rat†PMID 20054870Read ↗

Cytokeratin-19 positivity is acquired along cancer progression and does not predict cell origin in rat hepatocarcinogenesisSemantic proximity Read ↗

Hepatocellular carcinoma originates from hepatocytes and not from the progenitor/biliary compartmentSemantic proximity Read ↗

Murine Liver Organoids as a Genetically Flexible System to Study Liver Cancer In Vivo and In VitroSemantic proximity Read ↗

C/EBPα‐dependent preneoplastic tumor foci are the origin of hepatocellular carcinoma and aggressive pediatric liver cancerSemantic proximity Read ↗

Genetic and epigenetic control of molecular alterations in hepatocellular carcinoma.Semantic proximity Read ↗

Hepato-biliary profile of potential candidate liver progenitor cells from healthy rat liver.Semantic proximity Read ↗

Gene Expression Profile Related to the Progression of Preneoplastic Nodules toward Hepatocellular Carcinoma in RatsSemantic proximity Read ↗

Prognostic markers and putative therapeutic targets for hepatocellular carcinomaSemantic proximity Read ↗

Hepatocellular carcinoma as a complex polygenic disease. Interpretive analysis of recent developments on genetic predisposition.Semantic proximity Read ↗

Induction of autophagy promotes the growth of early preneoplastic rat liver nodulesSemantic proximity Read ↗

Remarkable heterogeneity displayed by oval cells in rat and mouse models of stem cell-mediated liver regeneration.Semantic proximity Read ↗

The Good, the Bad, the Question–H19 in Hepatocellular CarcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.