SLC22A3 polymorphisms do not modify pancreatic cancer risk, but may influence overall patient survival.

doi:10.1038/srep43812

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Article

SLC22A3 polymorphisms do not modify pancreatic cancer risk, but may influence overall patient survival.

Scientific reports - 8 Mar 2017

Mohelnikova-Duchonova Beatrice, Strouhal Ondrej, Hughes David J, Holcatova Ivana, Oliverius Martin, Kala Zdenek, Campa Daniele, Rizzato Cosmeri, Canzian Federico, Pezzilli Raffaele, Talar-Wojnarowska Renata, Malecka-Panas Ewa, Sperti Cosimo, Federico Zambon Carlo, Pedrazzoli Sergio, Fogar Paola, Milanetto Anna Caterina, Capurso Gabriele, Delle Fave Gianfranco, Valente Roberto, Gazouli Maria, Malleo Giuseppe, Teresa Lawlor Rita, Strobel Oliver, Hackert Thilo, Giese Nathalia, Vodicka Pavel, Vodickova Ludmila, Landi Stefano, Tavano Francesca, Gioffreda Domenica, Piepoli Ada, Pazienza Valerio, Mambrini Andrea, Pedata Mariangela, Cantore Maurizio, Bambi Franco, Ermini Stefano, Funel Niccola, Lemstrova Radmila, Soucek Pavel

Abstract excerpt

Expression of the solute carrier (SLC) transporter SLC22A3 gene is associated with overall survival of pancreatic cancer patients. This study tested whether genetic variability in SLC22A3 associates with pancreatic cancer risk and prognosis. Twenty four single nucleotide polymorphisms (SNPs) tagging the SLC22A3 gene sequence and regulatory elements were selected for analysis. Of these, 22 were successfully...

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PMID: 28272475
DOI: 10.1038/srep43812
PMCID: PMC5341046

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Source receipt: pubmed, retrieved 7 Sept 2026.

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