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Article

Glutathione S-transferase gene polymorphisms and risk and survival of pancreatic cancer.

Cancer - 1 Mar 2007

Jiao Li, Bondy Melissa L, Hassan Manal M, Chang David Z, Abbruzzese James L, Evans Douglas B, Smolensky Michael H, Li Donghui

Abstract excerpt

BACKGROUND: Pancreatic cancer is a multifactorial disease with metastasis-prone and therapy-resistant nature. The authors hypothesized that genetic variants of glutathione S-transferase (GST) affect detoxification of carcinogens and anticancer agents in the human pancreas and, thus, the risk and survival of pancreatic cancer. METHODS: Genotypes of GSTM1, GSTT1, and GSTP1 were determined in 352 patients with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17265526
DOI: 10.1002/cncr.22468
PMCID: PMC1892189

Genes

GSTP1
GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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