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Article

A single nucleotide polymorphism of the cholecystokinin-B receptor predicts risk for pancreatic cancer.

Cancer biology & therapy - 1 Feb 2012

Smith Jill P, Harms John F, Matters Gail L, McGovern Christopher O, Ruggiero Francesca M, Liao Jiangang, Fino Kristin K, Ortega Emily E, Gilius Evan L, Phillips John A

Abstract excerpt

There currently are no tests available for early diagnosis or for the identification of patients at risk for development of pancreatic cancer. We report the discovery of single nucleotide polymorphism (SNP) in the cholecystokinin B receptor (CCKBR) gene predicts survival and risk of pancreatic cancer. Growth of human pancreatic cancer is stimulated by gastrin through the CCKBR and an alternatively spliced isoform...

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Source

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Identifiers

PMID: 22277584
DOI: 10.4161/cbt.13.3.18698
PMCID: PMC3336072

Genes

CCKBR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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