Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SSTR5 P335L monoclonal antibody differentiates pancreatic neuroendocrine neuroplasms with different SSTR5 genotypes.

Surgery - 1 Dec 2011

Zhou Guisheng, Gingras Marie-Claude, Liu Shi-He, Sanchez Robbi, Edwards Dean, Dawson David, Christensen Kurt, Paganelli Giovanni, Gibbs Richard, Fisher William, Brunicardi Francis C

Abstract excerpt

BACKGROUND: Somatostatin receptor type 5 (SSTR5) P335L is a hypofunctional, single nucleotide polymorphism of SSTR5 with implications in the diagnostics and therapy of pancreatic neuroendocrine neoplasms. The purpose of this study is to determine whether a SSTR5 P335L-specific monoclonal antibody could sufficiently differentiate pancreatic neuroendocrine neoplasms (PNENs) with different SSTR5 genotypes. METHODS:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Monoclonal, Murine-Derived
Share to Blotting, Western

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Line, Tumor

Share to Immunohistochemistry

Share to Neuroendocrine Tumors

Share to Pancreatic Neoplasms

Share to Receptors, Somatostatin

Share to Reverse Transcriptase Polymerase Chain Reaction

Source

Open in PubMed Open full text

Identifiers

PMID: 22136833
DOI: 10.1016/j.surg.2011.09.044
PMCID: PMC3233698

Genes

SSTR5

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SSTR5 P335L monoclonal antibody differentiates pancreatic neuroendocrine neuroplasms with different SSTR5 genotypes.PMID 22136833Read ↗

The hypofunctional effect of P335L single nucleotide polymorphism on SSTR5 function.Semantic proximity Read ↗

Association between somatostatin receptor 5 gene polymorphisms and pancreatic cancer risk and survival.Semantic proximity Read ↗

The oncogenic role of the spliced somatostatin receptor sst5TMD4 variant in prostate cancerSemantic proximity Read ↗

Negative regulation of pancreatic and duodenal homeobox-1 by somatostatin receptor subtype 5.Semantic proximity Read ↗

Identification of somatostatin receptor type 5 gene polymorphisms associated with acromegaly.Semantic proximity Read ↗

Truncated somatostatin receptors as new players in somatostatin–cortistatin pathophysiologySemantic proximity Read ↗

Somatostatin Receptor Based Imaging and Radionuclide TherapySemantic proximity Read ↗

Genetic variation in the SST gene and its receptors in relation to circulating levels of insulin-like growth factor-I, IGFBP3, and prostate cancer risk.Semantic proximity Read ↗

Genetic abnormalities of somatostatin receptors in pituitary tumors.Semantic proximity Read ↗

Discovery of an SSTR2-Targeting Maytansinoid Conjugate (PEN-221) with Potent Activity in Vitro and in VivoSemantic proximity Read ↗

FGFR4 polymorphic alleles modulate mitochondrial respiration: A novel target for somatostatin analog action in pituitary tumors.Semantic proximity Read ↗

A phase 2 study of the insulin-like growth factor-1 receptor inhibitor MK-0646 in patients with metastatic, well-differentiated neuroendocrine tumors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.