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Article

Catechol-O-methyltransferase (COMT) Val158Met polymorphism and risk of osteoporotic fracture.

Molecular biology reports - 1 Mar 2012

Cao Yang, Wang Dawei, Liu Bin, Yao Guijun, Fu Yutuo, Bi Zhenggang

Abstract excerpt

Catechol-O-methyltransferase (COMT) is an estrogen degrading enzyme. The COMT Val158Met polymorphism is associated with bone mineral density. The aim of this study was to investigate associations between COMT Val158Met and osteoporotic fractures in Chinese Han patients. Case-control study of 320 patients with osteoporotic fractures and 320 healthy controls were conducted. The COMT Val158Met polymorphism was...

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Source

Identifiers

PMID: 21691708
DOI: 10.1007/s11033-011-1059-9

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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