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Article

Catechol O-methyltransferase val158-met polymorphism is associated with abdominal obesity and blood pressure in men.

Metabolism: clinical and experimental - 1 May 2008

Annerbrink Kristina, Westberg Lars, Nilsson Staffan, Rosmond Roland, Holm Göran, Eriksson Elias

Abstract excerpt

Catechol O-methyltransferase (COMT) degrades catecholamines and estrogens, both of which are of known importance for cardiovascular risk factors such as obesity and hypertension. The gene coding for COMT contains a val158-met polymorphism that exerts a considerable influence on enzymatic activity. We hypothesized that this polymorphism might influence risk factors for cardiovascular disease. Deoxyribonucleic acid...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18442637
DOI: 10.1016/j.metabol.2008.01.012

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Catechol O-methyltransferase val158-met polymorphism is associated with abdominal obesity and blood pressure in men.PMID 18442637Read ↗

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