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Article

The associations between the Val158Met in the catechol-O-methyltransferase (COMT) gene and the risk of uterine leiomyoma (ULM).

Gene - 25 Oct 2013

Feng Yi, Zhao Xitong, Zhou Chunfen, Yang Lu, Liu Yingwei, Bian Ce, Gou Jinhai, Lin Xiaojuan, Wang Zhenling, Zhao Xia

Abstract excerpt

The Val158Met polymorphism of the COMT gene has been implicated in susceptibility to uterine leiomyoma (ULM), but the reported results were inconclusive. The aim of the study was to evaluate the Val158Met polymorphism of the COMT gene and the risk of ULM by meta-analysis. A comprehensive electronic search for relevant articles was conducted in Pubmed, Embase, CNKI, Wanfang, and Weipu databases. Statistical...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23939469
DOI: 10.1016/j.gene.2013.07.019

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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The associations between the Val158Met in the catechol-O-methyltransferase (COMT) gene and the risk of uterine leiomyoma (ULM).PMID 23939469Read ↗

Polymorphism of catechol-o-methyltransferase and uterine leiomyoma.Semantic proximity Read ↗

Catechol-O-methyltransferase Val158Met polymorphism is associated with increased risk of multiple uterine leiomyomas either positive or negative for MED12 exon 2 mutations.Semantic proximity Read ↗

Val153Met polymorphism of catechol-O-methyltransferase and prevalence of uterine leiomyomata.Semantic proximity Read ↗

Catechol-O-methyltransferase polymorphism is associated with increased uterine leiomyoma risk in different ethnic groups.Semantic proximity Read ↗

Contribution of catechol-O-methyltransferase Val158Met polymorphism to endometrial cancer risk in postmenopausal women: a meta-analysis.Semantic proximity Read ↗

Association study between catechol-O-methyltransferase polymorphisms and uterine leiomyomas in a Japanese population.Semantic proximity Read ↗

Catechol-O-methyltransferase Gene Polymorphism (Val158Met) and Development of Pre-eclampsia.Semantic proximity Read ↗

Lack of associations of the COMT Val158Met polymorphism with risk of endometrial and ovarian cancer: a pooled analysis of case-control studies.Semantic proximity Read ↗

[Polymorphism of catechol-O-methyltransferase gene in relation to the risk of endometrial cancer].Semantic proximity Read ↗

Association of COMT Val158Met polymorphism and breast cancer risk: an updated meta-analysis.Semantic proximity Read ↗

Significant association of catechol-O-methyltransferase Val158Met polymorphism with bladder cancer instead of prostate and kidney cancer.Semantic proximity Read ↗

The catechol-O-methyltransferase (COMT) gene polymorphism and prevalence of uterine fibroids.Semantic proximity Read ↗

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