Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Polymorphism of catechol-O-methyltransferase gene in relation to the risk of endometrial cancer].

Zhonghua fu chan ke za zhi - 1 Feb 2007

Zhao Xiao-Miao, Xie Mei-Qing, Yang Dong-Zi, Wang Liang-An, Li Shi-Jie, Zhuang Yan-Yan, Tang Xue-Lian

Abstract excerpt

OBJECTIVE: The 4- and 16-hydroxylated metabolites of estrogens have been implicated in carcinogenesis, whereas its 2-hydroxylated metabolites have been shown to have antiangiogenic effects. We aimed to examine whether the polymorphisms of catechol-O-methyltransferase (COMT) involved in the estrogen metabolism are associated with endometrial cancer risk. METHODS: Polymerase chain reaction-restrictive fragment...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Catechol O-Methyltransferase
Share to Endometrial Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Menopause

Share to Polymerase Chain Reaction

Share to Polymorphism, Restriction Fragment Length

Share to Regression Analysis

Share to Risk Factors

Source

Identifiers

PMID: 17442187

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Polymorphism of catechol-O-methyltransferase gene in relation to the risk of endometrial cancer].PMID 17442187Read ↗

Contribution of catechol-O-methyltransferase Val158Met polymorphism to endometrial cancer risk in postmenopausal women: a meta-analysis.Semantic proximity Read ↗

Catechol-O-methyltransferase and cytochrome P-450 1B1 polymorphisms and endometrial cancer risk: a meta-analysis.Semantic proximity Read ↗

Lack of associations of the COMT Val158Met polymorphism with risk of endometrial and ovarian cancer: a pooled analysis of case-control studies.Semantic proximity Read ↗

Catechol-O-methyltransferase Gene Polymorphism (Val158Met) and Development of Pre-eclampsia.Semantic proximity Read ↗

Polymorphic catechol-O-methyltransferase gene, soy isoflavone intake and breast cancer in postmenopausal women: a case-control study.Semantic proximity Read ↗

Polymorphic catechol-O-methyltransferase gene, duration of estrogen exposure, and breast cancer risk: a nested case-control study in Taiwan.Semantic proximity Read ↗

The associations between the Val158Met in the catechol-O-methyltransferase (COMT) gene and the risk of uterine leiomyoma (ULM).Semantic proximity Read ↗

Impact of Catechol-O-Methyltransferase Val 158Met (rs4680) Polymorphism on Breast Cancer Susceptibility in Asian PopulationSemantic proximity Read ↗

Polymorphism of catechol-o-methyltransferase and uterine leiomyoma.Semantic proximity Read ↗

Genetic susceptibility of catechol-O-methyltransferase polymorphism in Japanese patients with breast cancer.Semantic proximity Read ↗

Genetic polymorphism of catechol-O-methyltransferase and cytochrome P450c17α in preeclampsia.Semantic proximity Read ↗

Polymorphisms of the estrogen-metabolizing genes CYP17 and catechol-O-methyltransferase and risk of epithelial ovarian cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.