Article

Transposable elements generate regulatory novelty in a tissue-specific fashion

2018-02-20

Abstract excerpt

<h4>Background</h4> Transposable elements (TE) are an important source of evolutionary novelty in gene regulation. However, the mechanisms by which TEs contribute to gene expression are largely uncharacterized. <h4>Results</h4> Here, we leverage Roadmap and GTEx data to investigate the association of TEs with active and repressed chromatin in 24 tissues. We find 112 human TE types enriched in active regions of t...

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Literature Corpus work: 762502ac-b611-5eda-a55e-92bddc42f183
DOI: 10.1101/268771

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