Article
Transposable elements as tissue-specific enhancers in cancers of endodermal lineage
2022-12-16
Abstract excerpt
Transposable elements (TE) are repetitive genomic elements that harbor binding sites for human transcription factors (TF). A regulatory role for TEs has been suggested in embryonal development and diseases such as cancer but systematic investigation of their functions has been limited by their widespread silencing in the genome. Here, we have utilized unbiased massively parallel reporter assay data using whole hum...
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Identifiers and source
- Literature Corpus work
- f84e5bce-5866-590b-8536-af0a76e43822
- DOI
- 10.1101/2022.12.16.520732