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Article

Species-specific substrate interaction of picornavirus 3C proteinase suballelic exchange mutants.

The Journal of biological chemistry - 15 Sept 1990

Lawson M A, Dasmahapatra B, Semler B L

Abstract excerpt

The substrate recognition properties of the polio-virus type 1 and coxsackievirus B3 3C proteinases have been examined in vitro by allelic and suballelic exchange of 3C between the cloned virus genomes. The activity of the altered 3C proteinases was examined by translation of synthetic RNA in a r...

Topics

Alleles
Animals
Cloning, Molecular
Cysteine Endopeptidases
Enterovirus B, Human
Escherichia coli
Genes, Viral
Mutation
Picornaviridae
Plasmids
Poliovirus
Protein Biosynthesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Rabbits

Restriction Mapping

Reticulocytes

Species Specificity

Transcription, Genetic

Source

Identifiers

PMID: 2168426

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2168426-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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