Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Antidepressant treatment is associated with epigenetic alterations in the promoter of P11 in a genetic model of depression

20 Jun 2011

Abstract excerpt

P11 (S100A10) has been associated with the pathophysiology of depression both in human and rodent models. Different types of antidepressants have been shown to increase P11 levels in distinct brain regions and P11 gene therapy was recently proven effective in reversing depressive-like behaviours in mice. However, the molecular mechanisms that govern P11 gene expression in response to antidepressants still remain...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Birth, Development, and Health
Share to Epigenetics and DNA Methylation
Share to Genetics and Neurodevelopmental Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21682946
DOI: 10.1017/s1461145711000940

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Antidepressant treatment is associated with epigenetic alterations in the promoter of P11 in a genetic model of depressionPMID 21682946Read ↗

DNA Methylation in Depression and Depressive-Like Phenotype: Biomarker or Target of Pharmacological Intervention?Semantic proximity Read ↗

P11 promoter methylation predicts the antidepressant effect of electroconvulsive therapySemantic proximity Read ↗

Expression Profiling of a Genetic Animal Model of Depression Reveals Novel Molecular Pathways Underlying Depressive-Like BehavioursSemantic proximity Read ↗

Allele-specific programming of Npy and epigenetic effects of physical activity in a genetic model of depression.Semantic proximity Read ↗

Phf8 loss confers resistance to depression-like and anxiety-like behaviors in mice.Semantic proximity Read ↗

Association study of p11 gene with major depressive disorder, suicidal behaviors and treatment response.Semantic proximity Read ↗

MicroRNA 101b Is Downregulated in the Prefrontal Cortex of a Genetic Model of Depression and Targets the Glutamate Transporter SLC1A1 (EAAT3) in Vitro.Semantic proximity Read ↗

TrkB-dependent antidepressants action involves Dlx5/6 inhibition in cortical GABAergic neurons.Semantic proximity Read ↗

Convergent animal and human evidence suggests a role of PPM1A gene in response to antidepressants.Semantic proximity Read ↗

[Epigenetic mechanisms in major depression].Semantic proximity Read ↗

DNA Methylation of POMC and NR3C1-1F and Its Implication in Major Depressive Disorder and Electroconvulsive TherapySemantic proximity Read ↗

Investigating the role of p11 (S100A10) sequence variation in susceptibility to major depression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.