Article

Dissecting the role of RNA-binding proteins in early herpes simplex virus 1 transcription using acute protein depletion

2025-02-11

Abstract excerpt

Herpes simplex virus 1 (HSV-1) infects about 50-80% of the entire human population and persists in the neurons of affected individuals. A fraction of affected individuals suffer from recurrent cold sores caused by reactivating virus, in rare but severe cases the virus can cause encephalitis. During lytic infection, the virus relies on host factors such as RNA polymerase II and accessory proteins involved in transc...

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Literature Corpus work: f5f96bbf-9610-50a2-8666-b1c1fdac38c6
DOI: 10.1101/2025.02.10.637450

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