Characterization of a herpes simplex virus type 1 deletion variant (1703) which under-produces Vmw63 during immediate early conditions of infection.

doi:10.1099/0022-1317-75-5-1083

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Article

Characterization of a herpes simplex virus type 1 deletion variant (1703) which under-produces Vmw63 during immediate early conditions of infection.

The Journal of general virology - 1 May 1994

Sinclair M C, McLauchlan J, Marsden H, Brown S M

Abstract excerpt

The herpes simplex virus type 1 deletion variant 1703 apparently fails to synthesize the essential IE2 gene product Vmw63 despite the deletion leaving the gene intact. Sequence analysis revealed that the deletion removes a region to the right of IE2 comprising the 3' end of IE1, UL56 and the 3' p...

Topics

Amino Acid Sequence
Down-Regulation
Gene Expression Regulation, Viral
Genetic Variation
Herpesvirus 1, Human
Immediate-Early Proteins
Molecular Sequence Data
Poly A
Promoter Regions, Genetic
RNA, Antisense
RNA, Messenger
Reading Frames
Sequence Analysis, DNA
Sequence Deletion
Single-Strand Specific DNA and RNA Endonucleases

Source

Open in PubMed

Identifiers

PMID: 7909833
DOI: 10.1099/0022-1317-75-5-1083

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7909833-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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