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Article

Neuronal function and dysfunction of Drosophila dTDP.

PloS one - 1 Jan 2011

Lin Meng-Jau, Cheng Ching-Wei, Shen C-K James

Abstract excerpt

BACKGROUND: TDP-43 is an RNA- and DNA-binding protein well conserved in animals including the mammals, Drosophila, and C. elegans. In mammals, the multi-function TDP-43 encoded by the TARDBP gene is a signature protein of the ubiquitin-positive inclusions (UBIs) in the diseased neuronal/glial cells of a range of neurodegenerative diseases including amyotrophic lateral sclerosis (ALS) and frontotemporal lobar...

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Identifiers

PMID: 21673800
DOI: 10.1371/journal.pone.0020371
PMCID: PMC3105987

Genes

TARDBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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