Article
Depletion of TDP-43 affects Drosophila motoneurons terminal synapsis and locomotive behavior.
FEBS letters - 19 May 2009
Feiguin Fabian, Godena Vinay K, Romano Giulia, D'Ambrogio Andrea, Klima Raffaella, Baralle Francisco E
Abstract excerpt
Pathological modifications in the highly conserved and ubiquitously expressed heterogeneous ribonucleoprotein TDP-43 were recently associated to neurodegenerative diseases including amyotrophic lateral sclerosis (ALS), a late-onset disorder that affects predominantly motoneurons [Neumann, M. et a...
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