Article
Efficient inducible Pan-neuronal cre-mediated recombination in SLICK-H transgenic mice.
Genesis (New York, N.Y. : 2000) - 1 Dec 2011
Heimer-McGinn Victoria, Young Paul
Abstract excerpt
Large-scale functional genomics in mice is becoming feasible through projects to develop conditional knockout alleles for every gene. Inducible neuron-specific gene knockout in such mice will permit the analysis of neuronal phenotypes while circumventing developmental defects or embryonic lethality. Here we describe a transgenic line, termed SLICK-H, that facilitates widespread inducible conditional genetic...
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