Article
Generating mosaics for lineage analysis in flies.
Wiley interdisciplinary reviews. Developmental biology - 1 Jan 2000
Lee Tzumin
Abstract excerpt
By generating and studying mosaic organisms, we are learning how intricate tissues form as cells proliferate and diversify through organism development. FLP/FRT-mediated site-specific mitotic recombination permits the generation of mosaic flies with efficiency and control. With heat-inducible or tissue-specific FLP transgenes at our disposal, we can engineer mosaics carrying clones of homozygous cells that come...
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