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Article

Comparative analysis of potential broad-spectrum neuronal Cre drivers

2022-07-08

Abstract excerpt

Cre/Lox technology is a powerful tool in the mouse genetics tool-box as it enables tissue-specific and inducible mutagenesis of specific gene loci. Correct interpretation of phenotypes depends upon knowledge of the Cre expression pattern in the chosen mouse driver line to ensure that appropriate cell types are targeted. For studies of the brain and neurological disease a pan-neuronal promoter that reliably drives...

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Literature Corpus work
298a53ee-51b2-54cc-99f4-99f8dc80a25f
DOI
10.12688/wellcomeopenres.17965.1
Open publication

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Comparative analysis of potential broad-spectrum neuronal Cre driversDOI 10.12688/wellcomeopenres.17965.1
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