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Article

Transcript specificity in yeast pre-mRNA splicing revealed by mutations in core spliceosomal components.

PLoS biology - 1 Apr 2007

Pleiss Jeffrey A, Whitworth Gregg B, Bergkessel Megan, Guthrie Christine

Abstract excerpt

Appropriate expression of most eukaryotic genes requires the removal of introns from their pre-messenger RNAs (pre-mRNAs), a process catalyzed by the spliceosome. In higher eukaryotes a large family of auxiliary factors known as SR proteins can improve the splicing efficiency of transcripts containing suboptimal splice sites by interacting with distinct sequences present in those pre-mRNAs. The yeast...

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Identifiers

PMID: 17388687
DOI: 10.1371/journal.pbio.0050090
PMCID: PMC1831718

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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