Article
Introns regulate RNA and protein abundance in yeast.
Genetics - 1 Sept 2006
Juneau Kara, Miranda Molly, Hillenmeyer Maureen E, Nislow Corey, Davis Ronald W
Abstract excerpt
The purpose of introns in the architecturally simple genome of Saccharomyces cerevisiae is not well understood. To assay the functional relevance of introns, a series of computational analyses and several detailed deletion studies were completed on the intronic genes of S. cerevisiae. Mining existing data from genomewide studies on yeast revealed that intron-containing genes produce more RNA and more protein and...
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