Article
A panoramic view of yeast noncoding RNA processing.
Cell - 27 Jun 2003
Peng Wen Tao, Robinson Mark D, Mnaimneh Sanie, Krogan Nevan J, Cagney Gerard, Morris Quaid, Davierwala Armaity P, Grigull Jörg, Yang Xueqi, Zhang Wen, Mitsakakis Nicholas, Ryan Owen W, Datta Nira, Jojic Vladimir, Pal Chris, Canadien Veronica, Richards Dawn, Beattie Bryan, Wu Lani F, Altschuler Steven J, Roweis Sam, Frey Brendan J, Emili Andrew, Greenblatt Jack F, Hughes Timothy R
Abstract excerpt
Predictive analysis using publicly available yeast functional genomics and proteomics data suggests that many more proteins may be involved in biogenesis of ribonucleoproteins than are currently known. Using a microarray that monitors abundance and processing of noncoding RNAs, we analyzed 468 yeast strains carrying mutations in protein-coding genes, most of which have not previously been associated with RNA or...
Topics
- Cells, Cultured
- Fungal Proteins
- Gene Expression Regulation, Fungal
- Genome, Fungal
- Mutation
- Oligonucleotide Array Sequence Analysis
- Phenotype
- RNA Precursors
- RNA, Small Nucleolar