Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genomewide linkage study of modifiers of LRRK2-related Parkinson's disease.

Movement disorders : official journal of the Movement Disorder Society - 1 Sept 2011

Latourelle Jeanne C, Hendricks Audrey E, Pankratz Nathan, Wilk Jemma B, Halter Cheryl, Nichols William C, Gusella James F, Destefano Anita L, Myers Richard H, Foroud Tatiana

Abstract excerpt

Mutations in the leucine-rich repeat kinase 2 gene, located at 12q12, are the most common known genetic causes of Parkinson's disease. Studies of leucine-rich repeat kinase 2 mutation carriers have shown incomplete and age-dependent penetrance, and previous studies have suggested that inherited susceptibility factors may modify the penetrance of leucine-rich repeat kinase 2 mutations. Genomewide linkage to age of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Family Health

Share to Genetic Linkage

Share to Leucine-Rich Repeat Serine-Threonine Protein Kinase-2

Share to Parkinson Disease

Share to Principal Component Analysis

Share to Protein Serine-Threonine Kinases

Source

Open in PubMed Open full text

Identifiers

PMID: 21661047
DOI: 10.1002/mds.23781
PMCID: PMC3346677

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genomewide linkage study of modifiers of LRRK2-related Parkinson's disease.PMID 21661047Read ↗

Identification of genetic modifiers of age-at-onset for familial Parkinson's disease.Semantic proximity Read ↗

Genomewide Association Studies of LRRK2 Modifiers of Parkinson's Disease.Semantic proximity Read ↗

Genome-wide association studies of LRRK2 modifiers of Parkinson's diseaseSemantic proximity Read ↗

Baseline genetic associations in the Parkinson's Progression Markers Initiative (PPMI).Semantic proximity Read ↗

Population-specific frequencies for LRRK2 susceptibility variants in the Genetic Epidemiology of Parkinson's Disease (GEO-PD) Consortium.Semantic proximity Read ↗

A susceptibility gene for late-onset idiopathic Parkinson's disease.Semantic proximity Read ↗

Fine-mapping of Parkinson's disease susceptibility loci identifies putative causal variants.Semantic proximity Read ↗

Genome-wide scan linkage analysis for Parkinson's disease: the European genetic study of Parkinson's disease.Semantic proximity Read ↗

Fine-mapping of Parkinson’s disease susceptibility loci identifies putative causal variantsSemantic proximity Read ↗

DNM3 and genetic modifiers of age of onset in LRRK2 Gly2019Ser parkinsonism: a genome-wide linkage and association studySemantic proximity Read ↗

LRRK2 gene in Parkinson disease: mutation analysis and case control association study.Semantic proximity Read ↗

LRRK2 mutation analysis in Parkinson disease families with evidence of linkage to PARK8.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.