Article
Herpes simplex virus IgG Fc receptors induced using recombinant adenovirus vectors expressing glycoproteins E and I.
Virology - 1 Aug 1990
Hanke T, Graham F L, Lulitanond V, Johnson D C
Abstract excerpt
Evidence has been presented that herpes simplex virus (HSV) immunoglobulin (IgG) Fc receptors are composed of a complex of two glycoproteins, gE and gI. In previous studies, cells infected with HSV-1 mutants lacking either gE or gI bound lower levels of soluble IgG than cells infected with wild-type viruses suggesting that both gE and gI were required for IgG binding. We have reevaluated the Fc receptor activity...
Topics
- Adenoviridae
- Animals
- Antibodies, Monoclonal
- Antigens, Differentiation
- Cell Line
- Cell Membrane
- Gene Expression
- Genetic Vectors
- Immunoglobulin G
- Mutation
- Plasmids
