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Article

Herpes simplex virus type 1 evades the effects of antibody and complement in vivo.

Journal of virology - 1 Sept 2002

Lubinski John M, Jiang Ming, Hook Lauren, Chang Yueh, Sarver Chad, Mastellos Dimitrios, Lambris John D, Cohen Gary H, Eisenberg Roselyn J, Friedman Harvey M

Abstract excerpt

Herpes simplex virus type 1 (HSV-1) encodes a complement-interacting glycoprotein, gC, and an immunoglobulin G (IgG) Fc binding glycoprotein, gE, that mediate immune evasion by affecting multiple aspects of innate and acquired immunity, including interfering with complement components C1q, C3, C5, and properdin and blocking antibody-dependent cellular cytotoxicity. Previous studies evaluated the individual...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 12186907
DOI: 10.1128/jvi.76.18.9232-9241.2002
PMCID: PMC136467

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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