Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Herpes simplex virus type 1 glycoprotein H binds to alphavbeta3 integrins.

The Journal of general virology - 1 Jan 2005

Parry Christopher, Bell Susanne, Minson Tony, Browne Helena

Abstract excerpt

Glycoprotein H (gH) homologues are found in all members of the herpes virus family, and gH is one of the virion envelope glycoproteins that is essential for virus entry. In this study, a recombinant soluble form of Herpes simplex virus type 1 (HSV-1) gH, in which the ectodomain is fused to the Fc-binding region of IgG, has been generated. This was expressed in mammalian cells together with gL and the resulting...

Topics

Animals
CHO Cells
Chlorocebus aethiops
Cricetinae
Integrin alphaVbeta3
Mutation
Protein Binding
Protein Structure, Tertiary
Recombinant Proteins
Simplexvirus
Vero Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Viral Envelope Proteins

Source

Identifiers

PMID: 15604426
DOI: 10.1099/vir.0.80567-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Herpes simplex virus type 1 glycoprotein H binds to alphavbeta3 integrins.PMID 15604426Read ↗

Dissociation of HSV gL from gH by αvβ6- or αvβ8-integrin promotes gH activation and virus entry.Semantic proximity Read ↗

Glycoprotein L disruption reveals two functional forms of the murine gammaherpesvirus 68 glycoprotein H.Semantic proximity Read ↗

Domains of glycoprotein H of herpes simplex virus type 1 involved in complex formation with glycoprotein L.Semantic proximity Read ↗

N-terminal mutants of herpes simplex virus type 2 gH are transported without gL but require gL for function.Semantic proximity Read ↗

Human Adenovirus Type 37 Uses αVβ1and α3β1Integrins for Infection of Human Corneal CellsSemantic proximity Read ↗

Human herpesvirus 8 envelope glycoprotein B mediates cell adhesion via its RGD sequence.Semantic proximity Read ↗

Crystal Structure of the Human Cytomegalovirus Glycoprotein BSemantic proximity Read ↗

Construction and properties of a mutant of herpes simplex virus type 1 with glycoprotein H coding sequences deleted.Semantic proximity Read ↗

The Neutralizing Linear Epitope of Human Herpesvirus 6A Glycoprotein B Does Not Affect Virus Infectivity.Semantic proximity Read ↗

Glycoprotein B plays a predominant role in mediating herpes simplex virus type 2 attachment and is required for entry and cell-to-cell spread.Semantic proximity Read ↗

Glycoprotein H of Human Cytomegalovirus (HCMV) Forms a Stable Complex With The HCMV UL115 Gene ProductSemantic proximity Read ↗

Identification and characterization of glycoprotein gH of human herpesvirus-6.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.