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Article

Modeling the functional genomics of autism using human neurons.

Molecular psychiatry - 1 Feb 2012

Konopka G, Wexler E, Rosen E, Mukamel Z, Osborn G E, Chen L, Lu D, Gao F, Gao K, Lowe J K, Geschwind D H

Abstract excerpt

Human neural progenitors from a variety of sources present new opportunities to model aspects of human neuropsychiatric disease in vitro. Such in vitro models provide the advantages of a human genetic background combined with rapid and easy manipulation, making them highly useful adjuncts to animal models. Here, we examined whether a human neuronal culture system could be utilized to assess the transcriptional...

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PMID: 21647150
DOI: 10.1038/mp.2011.60
PMCID: PMC3170664

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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