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Article

Characterization of sublines of HL-60 human leukemia cells resistant to induction of differentiation by butyric acid.

Leukemia - 1 Apr 1990

Fischkoff S A, Hoessly M C, Rossi R M

Abstract excerpt

HL-60 human leukemia cells undergo terminal differentiation when cultured with butyric acid. To produce cells resistant to the maturation-inducing effects of butyric acid, two strategies were followed. First, HL-60 cells were mutagenized and cultured in soft agar with inducing concentrations of butyric acid. Four clones were isolated resistant to a wide variety of differentiation inducers, including butyric acid....

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PMID: 2164121

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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