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Article

Low glutamine concentrations induce phenotypical and functional differentiation of U937 myelomonocytic cells.

The Journal of nutrition - 1 Nov 1997

Spittler A, Oehler R, Goetzinger P, Holzer S, Reissner C M, Leutmezer F, Rath V, Wrba F, Fuegger R, Boltz-Nitulescu G, Roth E

Abstract excerpt

L-Glutamine is the most abundant free amino acid of the human body and is essential for the culture of many cell types. Clinically, reduction of glutamine by administration of glutaminase or the use of glutamine analogs is a common therapy for patients with acute lymphocytic leukemia. In the current study, we investigated the influence of glutamine concentrations on the human myelomonocytic cell line U937....

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Identifiers

PMID: 9349841
DOI: 10.1093/jn/127.11.2151

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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