Article
Altered expression of cell cycle related genes including c-myb in a subclone of HL-60 that exhibits reversible differentiation.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research - 1 Jan 1992
Boise L H, Grant S, Westin E H
Abstract excerpt
A differentiation resistant subclone of HL-60, DMSOr, was removed from the selective pressure of dimethyl sulfoxide and characterized with a new stable phenotype of reversible differentiation. DMSOr cells, when treated with 1.25% dimethyl sulfoxide, differentiated in a manner similar to the paren...
Topics
- Base Sequence
- Blotting, Northern
- Cell Cycle
- Cell Differentiation
- Clone Cells
- Dimethyl Sulfoxide
- Gene Expression Regulation
- Humans
- Molecular Sequence Data
- Phenotype
- Proto-Oncogenes