The human promyelocytic HL60 cell line: a model of myeloid cell differentiation using dimethylsulphoxide, phorbol ester and butyrate.

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Article

The human promyelocytic HL60 cell line: a model of myeloid cell differentiation using dimethylsulphoxide, phorbol ester and butyrate.

Biochemistry international - 1 Feb 1991

Ahmed N, Williams J F, Weidemann M J

Abstract excerpt

The release of the reactive oxygen species that accompanies the oxidative burst was studied in HL60 cells differentiated with either dimethylsulphoxide, butyrate or phorbol myristate acetate in order to establish the extent to which differentiated cells are phenotypically similar to human neutrophils, monocytes and macrophages. When phorbol myristate acetate was used as a stimulus, the rates of superoxide...

Topics

Butyrates
Butyric Acid
Cell Differentiation
Cytochrome c Group
Dimethyl Sulfoxide
Hematopoietic Stem Cells
Humans
Leukemia, Promyelocytic, Acute
Leukocytes, Mononuclear
Luminescent Measurements
Lysosomes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Models, Biological

Neutrophils

Nitroblue Tetrazolium

Oxidation-Reduction

Phenotype

Tetradecanoylphorbol Acetate

Tumor Cells, Cultured

Source

Open in PubMed

Identifiers

PMID: 1652248

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1652248-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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