Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Oxidized LDL receptor 1 (OLR1) as a possible link between obesity, dyslipidemia and cancer.

PloS one - 1 Jan 2011

Khaidakov Magomed, Mitra Sona, Kang Bum-Yong, Wang Xianwei, Kadlubar Susan, Novelli Giuseppe, Raj Vinay, Winters Maria, Carter Weleetka C, Mehta Jawahar L

Abstract excerpt

Recent studies have linked expression of lectin-like ox-LDL receptor 1 (OLR1) to tumorigenesis. We analyzed microarray data from Olr1 knockout (KO) and wild type (WT) mice for genes involved in cellular transformation and evaluated effects of OLR1 over-expression in normal mammary epithelial cells (MCF10A) and breast cancer cells (HCC1143) in terms of gene expression, migration, adhesion and transendothelial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Adhesion
Share to Dyslipidemias

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epithelial Cells

Share to Lipogenesis

Share to NF-kappa B

Share to Obesity

Share to Scavenger Receptors, Class E

Share to Wound Healing

Source

Open in PubMed Open full text

Identifiers

PMID: 21637860
DOI: 10.1371/journal.pone.0020277
PMCID: PMC3102697

Genes

OLR1
BCL2
CCND2
FASN
PPARA
TNFAIP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Oxidized LDL receptor 1 (OLR1) as a possible link between obesity, dyslipidemia and cancer.PMID 21637860Read ↗

A transcriptional signature and common gene networks link cancer with lipid metabolism and diverse human diseases.Semantic proximity Read ↗

LDL Receptor–Related Protein-1Semantic proximity Read ↗

Oxidized low density lipoprotein receptor 1 promotes lung metastases of osteosarcomas through regulating the epithelial-mesenchymal transition.Semantic proximity Read ↗

LOX-1 and Its Splice Variants: A New Challenge for Atherosclerosis and Cancer-Targeted Therapies.Semantic proximity Read ↗

Sterol regulatory element-binding protein 1 is required for ovarian tumor growthSemantic proximity Read ↗

LDL-cholesterol signaling induces breast cancer proliferation and invasionSemantic proximity Read ↗

The alternative NF-κB RelB subunit is a novel critical sensor of lipid metabolism to promote tumor developmentSemantic proximity Read ↗

Mutant p53-R280K hijacks SREBP1 to promote fatty acid synthesis and breast cancer progression via FASN.Semantic proximity Read ↗

Impact of Obesity-Related Endoplasmic Reticulum Stress on Cancer and Associated Molecular TargetsSemantic proximity Read ↗

Lectin-like oxidized low-density lipoprotein receptor-1 promotes endothelial dysfunction in LDL receptor knockout background.Semantic proximity Read ↗

Endothelial AGO1 Drives Vascular Inflammation and Atherosclerosis via a Non-Canonical Nuclear MechanismSemantic proximity Read ↗

Pro-atherogenic diet accelerates tumor growth in mice through IL-1β and myeloid cell-derived VEGF-ASemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.