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Article

Oxidized low density lipoprotein receptor 1 promotes lung metastases of osteosarcomas through regulating the epithelial-mesenchymal transition.

Journal of translational medicine - 12 Nov 2019

Jiang Long, Jiang Shanshan, Zhou Wenjie, Huang Jia, Lin Yongbin, Long Hao, Luo Qingquan

Abstract excerpt

BACKGROUND: Oxidized low density lipoprotein receptor 1 (OLR1), a type II membrane protein, has been identified as receptor for oxidized low-density lipoprotein. The current study firstly provided evidence that OLR1 regulated EMT and thus promoted lung metastases in osteosarcoma (OS). METHOD: All relevant experiments were conducted according to the manufacturer's protocols. In vivo tumor xenograft experiments...

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Source

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Identifiers

PMID: 31718700
DOI: 10.1186/s12967-019-2107-9
PMCID: PMC6852786

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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