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Article

Lectin-like oxidized low-density lipoprotein receptor-1 promotes endothelial dysfunction in LDL receptor knockout background.

Atherosclerosis. Supplements - 1 Nov 2017

Hofmann Anja, Brunssen Coy, Poitz David M, Langbein Heike, Strasser Ruth H, Henle Thomas, Ravens Ursula, Morawietz Henning

Abstract excerpt

OBJECTIVE: Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is the major receptor for oxidized LDL in endothelial cells. LOX-1 is highly expressed in atherosclerotic plaques. The impact of LOX-1 on development of endothelial dysfunction in large vessels in absence or presence of atherosclerosis-prone conditions has not been studied to date. METHODS: Mice with endothelial cell-specific LOX-1...

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Source

Identifiers

PMID: 29096854
DOI: 10.1016/j.atherosclerosissup.2017.05.020

Genes

LOX

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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