Article
Adenosine A2(A) receptor gene polymorphism (1976C>T) affects coronary flow reserve response during vasodilator stress testing in patients with non ischemic-dilated cardiomyopathy.
Pharmacogenetics and genomics - 1 Aug 2011
Andreassi Maria Grazia, Laghi Pasini Franco, Picano Eugenio, Capecchi Pier Leopoldo, Pompella Gerarda, Foffa Ilenia, Borghini Andrea, Sicari Rosa
Abstract excerpt
OBJECTIVES: Patients with non ischemic-dilated cardiomyopathy (DCM) are characterized by an activation of the adenosinergic system and reduced coronary flow reserve (CFR) evaluated by transthoracic Doppler echocardiography during vasodilator adenosinergic stress (dipyridamole administration). The aim of this study was to assess whether genetic polymorphisms (263C>T and 1976C>T) of the A2(A) receptor gene affect...
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