Article
Variation in the alpha2B-adrenoceptor gene as a risk factor for prehospital fatal myocardial infarction and sudden cardiac death.
Journal of the American College of Cardiology - 15 Jan 2003
Snapir Amir, Mikkelsson Jussi, Perola Markus, Penttilä Antti, Scheinin Mika, Karhunen Pekka J
Abstract excerpt
OBJECTIVES: Our aim was to corroborate the observed association between the deletion/deletion (DD) genotype of the insertion/deletion polymorphism in the alpha(2B)-adrenoceptor (AR) and increased risk for acute myocardial infarction (AMI), and to study whether this genotype also confers an increased risk for sudden cardiac death (SCD). BACKGROUND: Vasospasm has been suggested to play a role in AMI. Alpha(2)-AR...
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