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Article

Adrenergic receptor genotype influences heart failure severity and β-blocker response in children with dilated cardiomyopathy.

Pediatric research - 1 Feb 2015

Reddy Sushma, Fung Alan, Manlhiot Cedric, Tierney Elif Seda Selamet, Chung Wendy K, Blume Elizabeth, Kaufman Beth D, Goldmuntz Elizabeth, Colan Steven, Mital Seema

Abstract excerpt

BACKGROUND: Adrenergic receptor (ADR) genotypes are associated with heart failure (HF) and β-blocker response in adults. We assessed the influence of ADR genotypes in children with dilated cardiomyopathy (DCM). METHODS: Ninety-one children with advanced DCM and 44 with stable DCM were genotyped for three ADR genotypes associated with HF risk in adults: α2cdel322-325, β1Arg389, and β2Arg16. Data were analyzed by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25406899
DOI: 10.1038/pr.2014.183
PMCID: PMC4298011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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