Article
Association of beta1-adrenergic receptor genetic polymorphism with mental stress-induced myocardial ischemia in patients with coronary artery disease.
Archives of internal medicine - 14 Apr 2008
Hassan Mustafa, York Kaki M, Li Haihong, Li Qin, Gong Yan, Langaee Taimour Y, Fillingim Roger B, Johnson Julie A, Sheps David S
Abstract excerpt
BACKGROUND: Mental stress is associated with sympathetic adrenergic stimulation and concomitant increases in blood pressure and heart rate. Heritable individual differences in cardiovascular functional response to mental stress may arise from genetic variations in adrenergic receptors, which might produce excessive hemodynamic response to mental stress or create other conditions favoring the development of...
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