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Article

Multigenic control and sex bias in host susceptibility to spore-induced pulmonary anthrax in mice.

Infection and immunity - 1 Aug 2011

Yadav Jagjit S, Pradhan Suman, Kapoor Renuka, Bangar Hansraj, Burzynski Benjamin B, Prows Daniel R, Levin Linda

Abstract excerpt

Mechanisms underlying susceptibility to anthrax infection are unknown. Using a phylogenetically diverse panel of inbred mice and spores of Bacillus anthracis Ames, we investigated host susceptibility to pulmonary anthrax. Susceptibility profiles for survival time and organ pathogen load differed across strains, indicating distinct genetic controls. Tissue infection kinetics analysis showed greater systemic...

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Source

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Identifiers

PMID: 21628518
DOI: 10.1128/IAI.01389-10
PMCID: PMC3147590

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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