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Article

Rapid vascular responses to anthrax lethal toxin in mice containing a segment of chromosome 11 from the CAST/Ei strain on a C57BL/6 genetic background.

PloS one - 1 Jan 2012

Weigel Kelsey J, Rues Laura, Doyle Edward J, Buchheit Cassandra L, Wood John G, Gallagher Ryan J, Kelly Laura E, Radel Jeffrey D, Bradley Kenneth A, LeVine Steven M

Abstract excerpt

Host allelic variation controls the response to B. anthracis and the disease course of anthrax. Mouse strains with macrophages that are responsive to anthrax lethal toxin (LT) show resistance to infection while mouse strains with LT non-responsive macrophages succumb more readily. B6.CAST.11M mic...

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Source

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Identifiers

PMID: 22792226
DOI: 10.1371/journal.pone.0040126
PMCID: PMC3390349

Genes

CAST

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22792226-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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