Article
Genetic control of susceptibility to pulmonary infection with Chlamydia pneumoniae in the mouse.
Genes and immunity - 1 Jun 2008
Min-Oo G, Lindqvist L, Vaglenov A, Wang C, Fortin P, Li Y, Kaltenboeck B, Gros P
Abstract excerpt
A mouse model was used to study the genetic control of differential host response to pulmonary infection with Chlamydia pneumoniae. The A/J and C57BL/6 strains show differential response to intranasal infection with respect to their ability to clear pulmonary bacterial load and the extent of lung pathology developed by 2 weeks post infection. The genetic basis of this interstrain difference was studied by...
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