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Article

Inflammation and immune-related candidate gene associations with acute lung injury susceptibility and severity: a validation study.

PloS one - 1 Jan 2012

O'Mahony D Shane, Glavan Bradford J, Holden Tarah D, Fong Christie, Black R Anthony, Rona Gail, Tejera Paula, Christiani David C, Wurfel Mark M

Abstract excerpt

INTRODUCTION: Common variants in genes related to inflammation, innate immunity, epithelial cell function, and angiogenesis have been reported to be associated with risks for Acute Lung Injury (ALI) and related outcomes. We tested whether previously-reported associations can be validated in an independent cohort at risk for ALI. METHODS: We identified 37 genetic variants in 27 genes previously associated with ALI...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23251429
DOI: 10.1371/journal.pone.0051104
PMCID: PMC3522667

Genes

NAMPT
MBL2
MAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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