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Article

A genome-wide association study of testicular germ cell tumor.

Nature genetics - 1 Jul 2009

Rapley Elizabeth A, Turnbull Clare, Al Olama Ali Amin, Dermitzakis Emmanouil T, Linger Rachel, Huddart Robert A, Renwick Anthony, Hughes Deborah, Hines Sarah, Seal Sheila, Morrison Jonathan, Nsengimana Jeremie, Deloukas Panagiotis, Rahman Nazneen, Bishop D Timothy, Easton Douglas F, Stratton Michael R

Abstract excerpt

We conducted a genome-wide association study for testicular germ cell tumor (TGCT), genotyping 307,666 SNPs in 730 cases and 1,435 controls from the UK and replicating associations in a further 571 cases and 1,806 controls. We found strong evidence for susceptibility loci on chromosome 5 (per allele OR = 1.37 (95% CI = 1.19-1.58), P = 3 x 10(-13)), chromosome 6 (OR = 1.50 (95% CI = 1.28-1.75), P = 10(-13)) and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19483681
DOI: 10.1038/ng.394
PMCID: PMC2871592

Genes

KIT
KITLG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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